About

The NMR Facility at the University of Massachusetts Amherst is an interdepartmental facility, open to researchers of the Five Colleges Consortium (UMass Amherst, Smith, Mt. Holyoke, Amherst and Hampshire Colleges) and industries.  It supports research programs of ca. 36 groups in the areas of chemical synthesis, polymer chemistry, materials science, and natural products.

The facility oversees five NMR spectrometers:

  • Agilent 700MHz with Cold Probe®, specialized for biomacromolecule structure elucidation;
  • Bruker 600MHz with Cryoprobe® and a 60-position autosampler, suitable for both in-depth biomacromolecule structure study and high-throughput screening;
  • Bruker 600MHz with 1.9mm, 4mm, E-free, and Pisema solid-state probes, suitable for a wide range of solid-state NMR experiments, and a diffusion probe, specialized for studies of very slow diffusion of large molecules, micelles and aggregates;
  • Bruker 500MHz with Prodigy® cryoprobe and autosampler for open-access chemical structure determination;
  • Bruker 400MHz with Prodigy® cryoprobe and autosampler for open-access chemical structure determination.

Research Interest of Dr. Weiguo Hu:

Critical in many macroscopic properties, the profile of molecular dynamics in polymeric materials is complex, influenced by factors such as chain microstructure, morphology, and intermolecular interactions. With the ability to probe molecular dynamics with chemical and phase resolution, solid-state NMR is in a unique position to study this essential molecular trait. We employ and develop solid-state NMR techniques to study molecular dynamics and its relationship with chemical structure and assembly behavior, and inquire how it governs materials’ macroscopic properties such as those under extreme dynamic environments.

Recent Publications

  • “Modifying the Structure and Dynamics of Ionomers through Counterion Sterics”, J. S. Enokida, W. Hu, H. Fang, B. F. Morgan, F. L. Beyer, H. H. Winter, E. Bryan Coughlin, Macromolecules, 2020, 53, 1767-1776
  • “Molecular Dependencies of Dynamic Stiffening and Strengthening through High Strain Rate Microparticle Impact of Polyurethane and Polyurea Elastomers”, Y. Sun, Y.-C. M. Wu, D. Veysset, S. E. Kooi, W. Hu, T. M. Swager, K. A. Nelson, A. J. Hsieh, Appl. Phys. Lett. 2019, 115, 093701
  • 19F MRI of Polymer Nanogels Aided by Improved Segmental Mobility of Embedded Fluorine Moieties”, O. Munkhbat, M. Canakci, S. Zheng, W. Hu, B. Osborne, A. A. Bogdanov, and S. Thayumanavan, Biomacromolecules, 2019, 20(2), pp 790–800
  • “Unraveling the high strain-rate dynamic stiffening in select model polyurethanes − the role of intermolecular hydrogen bonding”, Y.-C. M. Wu, W. Hu, Y. Sun, D. Veysset, S. E. Kooi, K. A. Nelson, T. M. Swager, A. J. Hsieh, Polymer, 2019, 168, 218-227
  • “Functional polymers for growth and stabilization of CsPbBr3 perovskite nanoparticles”, H. Kim, S. So, A. Ribbe, Y. Liu, W. Hu, V. V. Duzhko, R. C. Hayward, and T. Emrick, Chem. Commun. 2019, 55, 1833-1836
  • “Characterization of High Polymerization Degree Ammonium Polyphosphate and Its Chain Structure by 31P NMR”, Y. Liu, R, Yang, D. Li, J. Liang, and W. Hu. ChemJ. Chin. Univ. 2018, 39, 2080-2088.
  • “Broadening the scope for fluoride-free synthesis of siliceous zeolites”, V. Vattipalli, A. M. Paracha, W. Hu, H. Chen, and W. Fan, AngewChem. Intl. Ed. 2018, 57, 1-6.
  • “Degradation Mechanism of Poly(p-phenylene-2,6-benzobisoxazole) Fibers by 31P Solid-State NMR”, N. Kanbargi, W. Hu, A. J. Lesser, Polymer Degradation and Stability, 2017, 136, 131-138
  • “New Insight into the Influence of Molecular Dynamics of Matrix Elastomers on Ballistic Impact Deformation in UHMWPE Composites”, A. J. Hsieh, T. L. Chantawansri, W. Hu, J. Cain, J. H. Yu, Polymer, 2016, 95, 52-61
  • “Glass transition of soft segments in phase-mixed poly(urethane urea) elastomers by time-domain 1H and 13C solid-state NMR”. W. Hu, N. V. Patil, A. J. Hsieh. Polymer, 2016, 100, 149-157
  • “Measuring the Degree of Crystallinity in Semicrystalline Regioregular Poly(3-hexylthiophene).” X. Shen, W. Hu, T. P. Russell. Macromolecules, 2016, 49, 4501-4509
  • “New Insight into Microstructure-Mediated Segmental Dynamics in Select Model   Poly(urethane urea) Elastomers”, A. J. Hsieh, T. L. Chantawansri, W. Hu et al., Polymer, 2014, 55, 1883-1892
  • “Phase-Mixing and Molecular Dynamics in Poly(urethane urea) Elastomers by Solid-State NMR”, W. Hu, A. J. Hsieh. Polymer, 2013, 54, 6218-6225
  • “Chemical structure changes in kerogen from bituminous coal in response to 1 dike intrusions as investigated by advanced solid-state 13C NMR spectroscopy.” X. Cao, M. Chappell, A. Schimmelmann, M. Mastalerz, Y. Li, W. Hu, J. Mao, Int. J. Coal Geology. 2013, 108, 53-64
  • “Interaction between Antimicrobial Oligomers and Membrane Studied by Solid-State NMR”, W. Hu, A. Som, G. N. Tew, J. Phys. Chem. B 2011, 115, 8474–8480.

Contact:

Weiguo Hu, Ph.D.
Director of Nuclear Magnetic Resonance Labs/Chemistry & Materials
University of Massachusetts
A328 Conte
120 Governors Dr.
Amherst, MA 01003
phone: 413 577 1428.  fax: 413 545 0082. mail: weiguoh at umass edu

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