1.Decalcified Histology

  • Used to determine biochemical composition
  • Study of cell morphology, glycosaminoglycan content

 

2. Nondecalcified Histology

  • Primarily used for characterizing soft tissue to bone interfaces
  • tidemark integrity, etc.

 

Some examples of histology staining through the native meniscal insertion. LI: Ligamentous Region, UF: Uncalcified Fibrocartilage, CF: Calcified Fibrocartilage, SB: Subchondral bone