Lab Alum, Fan Zhang, was awarded a Translational Medicine Research Starter Grant from the PhRMA Foundation. Congratulations Fan! Head over to her lab website to see some great new research and people in her lab.
Aaron Schein starting at University of Chicago in Fall 2022
Aaron Schein is moving to the University of Chicago as an assistant professor in the Department of Statistics and the Data Science Institute, in July 2022. Congratulations Aaron!
Paper: Model-based identification of conditionally-essential genes from transposon-insertion sequencing data
Our paper on transposon sequencing has been published in PLOS Computational Biology. The full article is available at here.
Summary: Transposon insertion sequencing allows the study of bacterial gene function by combining next-generation sequencing techniques with transposon mutagenesis under different genetic and environmental perturbations. Our proposed regularized negative binomial regression method improves the quality of analysis of this data.
Tingting Zhao starting at Bryant University in Spring 2022
Tingting Zhao is moving to the Bryant University as an assistant professor in the Department of Information Systems and Analytics, in January 2022. Congratulations Tingting!
bioRxiv preprint: Model-based identification of conditionally-essential genes from transposon-insertion sequencing data
Vishal Sarsani’s new paper describes a model-based method for identifying conditionally essential genes. There is an R package associated with the method. This work is with our wonderful collaborators in the Chien Lab at UMass. Thanks to NIH 5R01GM135931 for funding this work.