Lab Alum, Fan Zhang, was awarded a Translational Medicine Research Starter Grant from the PhRMA Foundation. Congratulations Fan! Head over to her lab website to see some great new research and people in her lab.
Our paper on transposon sequencing has been published in PLOS Computational Biology. The full article is available at here.
Summary: Transposon insertion sequencing allows the study of bacterial gene function by combining next-generation sequencing techniques with transposon mutagenesis under different genetic and environmental perturbations. Our proposed regularized negative binomial regression method improves the quality of analysis of this data.