UMass Neurosciences Publications – November 2022

Dr. Agnès Lacreuse

This month’s featured research is Dr. Agnès Lacreuse. Agnès is a Professor in the Department Psychological & Brain Sciences. Her work is focused on age-related cognitive decline in a nonhuman primate with a short lifespan, the common marmoset (C. jacchus). Research from her lab recently appeared in the journal, Hormones and Behavior, showing that Letrozole, an aromatase inhibitor used in breast cancer treatment, alters gene expression in neurons of the hippocampus, a region of the brain involved with memory. The first author on this intriguing study was Melise Edwards, a PhD student in the Neuroscience and Behavior Graduate Program.

Here’s what else is new for ‘ ”University of Massachusetts” AND Amherst AND neuroscience’ in PubMed. These publications appeared online in November. They are just a fraction of the neuroscience research that occurs on campus. You can click on the PubMed ID to find the publication.

1: Sadil P, Cowell RA, Huber DE. A modeling framework for determining modulation of neural-level tuning from non-invasive human fMRI data. Commun Biol. 2022 Nov 14;5(1):1244. doi: 10.1038/s42003-022-04000-9. PMID: 36376370; PMCID: PMC9663541.

2: Chow SM, …, Marlin B, …, Wolff-Hughes DL; Intensive Longitudinal Health Behavior Network (ILHBN). The ILHBN: challenges, opportunities, and solutions from harmonizing data under heterogeneous study designs, target populations, and measurement protocols. Transl Behav Med. 2022 Nov 23:ibac069. doi: 10.1093/tbm/ibac069. Epub ahead of print. PMID: 36416389.

3: Holec SAM, Lee J, Oehler A, Batia L, Wiggins-Gamble A, Lau J, Ooi FK, Merz GE, Wang M, Mordes DA, Olson SH, Woerman AL. The E46K mutation modulates α-synuclein prion replication in transgenic mice. PLoS Pathog. 2022 Dec 1;18(12):e1010956. doi: 10.1371/journal.ppat.1010956. PMID: 36454879.

4: Sato SD, Hiroi Y, Zoppo D, Buonaccorsi J, Miehm JD, van Emmerik REA. Spatiotemporal gait changes in people with multiple sclerosis with different disease progression subtypes. Clin Biomech (Bristol, Avon). 2022 Nov 12;100:105818. doi: 10.1016/j.clinbiomech.2022.105818. Epub ahead of print. PMID: 36435079.

5: Edwards M, Lam S, Ranjan R, Pereira M, Babbitt C, Lacreuse A. Letrozole treatment alters hippocampal gene expression in common marmosets (Callithrix jacchus). Horm Behav. 2022 Nov 23;147:105281. doi: 10.1016/j.yhbeh.2022.105281. Epub ahead of print. PMID: 36434852.

6: Ward CB, Mack JE. The effect of an aphasia ID card on the processing of language produced by a speaker with nonfluent aphasia. J Commun Disord. 2022 Nov-Dec;100:106268. doi: 10.1016/j.jcomdis.2022.106268. Epub 2022 Sep 19. PMID: 36137321.