See github or google scholar for upto date publications.

  1. Tatapudi, H. and Gopalappa, C., Evaluating the sensitivity of jurisdictional-heterogeneity and jurisdictional-mixing in national-level HIV prevention analyses: Context of the U.S. Ending the HIV Epidemic goal. PrePrint ; DOI: 10.21203/
  2. Khatami, N., and Gopalappa, C., A reinforcement learning model to inform optimal decision paths for HIV elimination, Mathematical Biosciences and Engineering, Volume 18, Issue 6: 7666-7684, 2021. doi: 10.3934/mbe.2021380, LINK
    • Finalist for student best paper poster competition, SMDM, 2018
  3. Zhao, X., Tatapudi, H., Corey, G., Gopalappa, C., Threshold analyses on combinations of testing, population size, and vaccine coverage for COVID-19 control in a university setting, PLoSOne, 2021 Ahead-of-Print
  4. Eden*, M., Castonguay*, R., Munkbat*, B., Balasubramanian, H., Gopalappa, C., Agent-based evolving network modeling: a new simulation method for modeling low prevalence infectious diseases, Health Care Management Science, 24, 623–639 (2021). LINK
    • Finalist best paper award, INFORMS, Operations Research track, 2018
  5. Singh*, S., France, A. M., Chen, Y-H, Farnham, P. G., Oster, A. M., Gopalappa, C., Progression and Transmission of HIV (PATH4.0): A new agent-based evolving network simulation for modeling HIV transmission clusters; Mathematical Biosciences and Engineering, 18 (3), 2021, LINK
    • Best paper award, Institute for Industrial and Systems Engineers (IISE), Simulation and Modeling track, 2021
    • Work in collaboration with the Centers for Disease Control and Prevention

  6. Shifali Bansal*, BS, Vijeta Deshpande*, MS, Xinmeng Zhao, BS, Jeremy A. Lauer, PhD, Filip  Meheus, PhD, André Ilbawi, MD, Chaitra Gopalappa1, PhD, Analysis of mammography screening schedules under varying resource constraints for planning breast cancer control programs in low- and middle- income countries: a mathematical study, Medical Decision Making, Vol. 40(3), 2020 PDF LINK

    • Work in collaboration with the World Health Organization (WHO) and Institute for Research on Cancer (IARC)
  7. Ambinintsoa H. Ralaidovy,  Chaitra  Gopalappa,  André  Ilbawi,  Carel  Pretorius and  Jeremy A. Lauer, Cost-effective interventions for breast cancer, cervical cancer, and colorectal cancer: new results from WHO-CHOICE, Cost Effectiveness and Resource Allocation, 18 (38), 2018 LINK LINK
    • Work in collaboration with the World Health Organization (WHO)
  8. Gopalappa, C., Guo*, J., Meckoni*, P., Munkhbat*, B., Pretorius, C., Lauer, J., Ilbawi, A., Bertram, M., A two-step Markov processes approach for parameterization of cancer state-transition models for low- and middle- income countries, Medical Decision Making, Vol. 38(4) 520–530, 2018, PDF technical-suppl LINK

    • Work in collaboration with the World Health Organization (WHO) and Avenir Health
    • Informed: 

      World Health Organization, Cancer Interventions Technical Briefing For The Updated (2017) Appendix 3 Of The Global Action Plan For The Prevention And Control Of Noncommunicable Diseases 2013-2020, LINK*

      World Health Organization, Best buys and other recommended interventions for the prevention and control of noncommunicable diseases, Updated (2017) appendix 3 of the global action plan for the prevention and control of noncommunicable diseases 2013-2020, LINK
  9. Gopalappa, C., Farnham, P.G., Chen, Y-H., and Sansom, S.L. Combinations of interventions to achieve a national HIV incidence reduction goal: insights from an agent-based model. AIDS, November 28, 2017 – Volume 31 – Issue 18 – p 2533 to 2539 LINK 

    • Work in collaboration with the Centers for Disease Control and Prevention
  10. Gopalappa, C., Farnham, P.G., Chen, Y-H., and Sansom, S.L. Progression and Transmission of HIV/AIDS (PATH 2.0): A New Agent-Based Model to Estimate HIV Transmissions in the United States, Med Decis Making 2017 Feb;37(2):224-233. doi: 10.1177/0272989X16668509 LINK

    • Work in collaboration with the Centers for Disease Control and Prevention
    • Cited in CDC’s Vital Signs

    • Dailey AF, Hoots BE, Hall HI, et al. Vital Signs: Human Immunodeficiency Virus Testing and Diagnosis Delays — United States. MMWR Morb Mortal Wkly Rep 2017;66:1300–1306. DOI:

  11. Eaton, J., Bacaër, N., Bershteyn, A., Cambiano, V., Cori, A., Dorrington, R.E., Fraser, C., Gopalappa, C., Hontelez, J.A.C., Johnson, L.F., Klein, D.J., Phillips, A.N., Pretorius, C., Stover, J., Rehle, T.M., Hallett, T.B., Assessment of epidemic projections using recent HIV survey data in South Africa: a validation analysis of ten mathematical models of HIV epidemiology in the antiretroviral therapy era, The Lancet Global Health, Vol 3, e598, October 2015; DOI:; LINK

  12. Stover, J., Andreev, K., Slaymaker, E., Gopalappa, C., Sabin, K., Velasquez, C., Nakiyingi-Miiro, J., Crampin, A., Lutalo, T., Herbst, K., Gregson, S., and Urassa, M., Updates to the Spectrum model to estimate key HIV indicators for adults and children, AIDS 2014, 28 (Suppl 4):S427–S434 PDF

  13. Gopalappa, C., Stover, J., Shaffer, N., and Mahy, M., The Costs and Benefits of Option B+ for the Prevention of Mother-to-Child Transmission of HIV, AIDS, 28 Suppl. 1:S5-14, 2014 LINK

  14. Stover, J., Hallett, T., Wu, Z., Warren, M., Gopalappa, C., Pretorius, C., Ghys, P.D., Montaner, J., Schwartländer, B.; New Prevention Technology Study Group, How can we go to Zero? The Potential Contribution of Biomedical Prevention and the Investment Framework towards an Effective Response to HIV, PLoS One, 9(11):e111956, 2014 PDF

  15. Stover, J., Gopalappa, C., Mahy, M., Doherty, M.C., Easterbrook, P.J., Weiler, G., and Ghys, P.D., The impact and cost of the 2013 WHO recommendations on eligibility for antiretroviral therapy, AIDS, 28 Suppl. 2:S225-30, 2014 PDF

  16. Gopalappa, C., Huang, Y., Melanie, T., Kwame, O., and Gift, T., Cost-effectiveness of screening men in Maricopa County jails for chlamydia and gonorrhea to avert infections in women, STD, 40 (10):776-783, 2013 MODEL

  17. Pretorius, C., Menzies, N.A., Chindelevitch, L., Cohen, T., Cori, A., Eaton, J. A., Fraser, C., Gopalappa, C., Hallett, T. B., Salomon, J. A., Stover, J., White, R. G., Dodd, P. J., The potential effects of changing HIV treatment policy on TB outcomes in South Africa: results from three TB-HIV transmission models, AIDS, 28 Suppl 1:S25-34, 2014

  18. Eaton, J., Menzies, N., Stover, J., Cambiano, V., Chindelevitch, L., Cori, A., Hontelez, J. A. C., Humair, S., Kerr C. C., Klein, D J., Mishra, S., Mitchell, K. M., Nichols, B.E., Vickerman, V., Bakker, R., Barnighausen, T., Bershteyn, A., Bloom, D.E., Boily, M-C, Chang, S.T., Cohen, T., Dodd, P.J., Fraser, C., Gopalappa, C., Lundgren, J., Martin, N.K., Mikkelsen, E., Mountain, E., Pham, Q.D., Pickles, M., Phillips, A., Platt, L., Pretorius, C., Prudden, H.J., Salomon, J.A., van de Vijver, D.A.M.C., de Vlas, S. J., Wagner, B. G., White, R.G., Wilson, D.P., Zhang, L., Blandford, J., Meyer-Rath, G., Remme, M., Revill, P., Sangrujee, N., Terris-Prestholt, F., Doherty, M., Shaffer, N., Easterbrook, P.J., Hirnschall, G., Hallett, T.B., How should HIV programmes respond to evidence for the benefits of earlier treatment initiation? A combined analysis of twelve mathematical models, Lancet Global Health, 2(1):e23, 2014

  19. Farnham, P., Gopalappa, C., Sansom, S., Updates of lifetime costs of care and quality-of-life estimates for HIV-infected persons in the United States: late versus early diagnosis and entry into care, JAIDS, 64(2):183-189, 2013. MODEL

  20. Farnham, P.G., Holtgrave, D. R., Gopalappa, C., Angela B. Hutchinson, Stephanie L. Sansom, Lifetime Costs and QALYs Saved from HIV Prevention in the Test and Treat Era, Letter to the Editor, JAIDS, 64(2):e15-e18, 2013

  21. Gopalappa, C., Stover, J., and Pretorius, C., HIV prevalence patterns by age: Exploring differences among 19 countries, DHS Analytical Studies, No. 40. Calverton, Maryland, USA: ICF International, 2013.

  22. Gopalappa, C., Farnham, P., Hutchinson, A., and Sansom, S., Cost-effectiveness of the National HIV/AIDS Strategy (NHAS) goal of increasing the proportion linking to care at diagnosis, JAIDS, 61 (1):99-105, 2012.

  23. Gopalappa, C., Cremaschi, S., Das, T., Orcun, S., Applied Probability Models for Estimating Progression Rates between Colorectal Cancer Stages, Health Care Management Science 14(1), March 2011: Pg 1-21 pdf

    • Institute of Industrial Engineers (IIE) Pritsker Doctoral Dissertation Award

  24. Gopalappa, C., Das, T., Enkemann, S., and Eschrich, S., Removal of Hybridization and Scanning Noise from Microarrays, IEEE Transactions on Nanobioscience, 8(3), 2009